The 2010 season of the Caisse d'Épargne cycling team is the thirty-first season since the creation of the Reynolds team in 1980 and the fourth under this name. Caisse d'Épargne has had the status of a ProTour team since 2005. This season is marked by the two-year suspension pronounced in May against Alejandro Valverde, effective January 1, 2010. This decision results in the cancellation of the results obtained by Valverde at the beginning of the season, including in particular his victory in the Tour de Romandie. In the absence of Valverde, Luis León Sánchez is the main leader of the team. He finishes in third place in the world rankings and wins in particular the Classic of San Sebastián and the Spanish time trial championship.

The French bank Caisse d'Epargne announced at the beginning of the year its intention not to continue its sponsorship activity beyond 2010. The name of the new main sponsor for the 2011 season, Movistar, was announced in August.